Evaluation Of Antiemetic Potential Of Aqueous Bark Extract Of Cinnamon Loureiroi

Abstract

Crude aqueous bark extract of Cinnamon  loureiroi. was evaluated for anti-emetic potential. Emesis was induced by the oral administration of copper sulphate and fresh aqueous extract of Brassica compestris to male chicks of fifteen days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. Cinnamon (3 and 6 mg / kg body weight orally) showed anti-emetic activity when compared with standard drugs Chlorpromazine , Domperidone and Metoclopramide. Both the extracts, showed the antiemetic activity, highest (79.22% inhibition) and the lowest (58. 94 % inhibition) in copper sulphate induced emesis and highest  (81.91% ) and the lowest( 59.57%) in  Brassica compestris induced emesis .