While most scholars acknowledge the fact that there are a thousand years missing from the History of Science, but only, some relate the missing link to the Islamic world founded on the principles and guidelines of the Holy Quran. Therefore, there is a need to methodically study the effects of the Holy Quran on the history of science. This research article tries to suggest reasons for the scholarly neglect shown towards the contributions of the Holy Quran. Lastly, it will explore how the Holy Quran paved the way to the world of modern Science.